Distinguishing the Forces Controlling Variation at the Xdh Locus in Drosophila Pseudoobscura
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منابع مشابه
Distinguishing the forces controlling genetic variation at the Xdh locus in Drosophila pseudoobscura.
Fifty-eight isochromosomal lines sampled from two natural populations of Drosophila pseudoobscura in California and one from Bogota, Colombia, were examined using four-cutter restriction mapping. A 4.6-kb region of the xanthine dehydrogenase locus was probed and 66 of 135 restriction sites scored were polymorphic. This predicts that on average every 12th bp would be polymorphic in this region f...
متن کاملNucleotide polymorphism at the xanthine dehydrogenase locus in Drosophila pseudoobscura.
Sequential polyacrylamide electrophoresis has revealed 20 allozymes of xanthine dehydrogenase (XDH) in Drosophila pseudoobscura. DNA sequence determination of seven isolates of the Xdh locus that represent six allozyme classes are presented here. Of the 5,456 sites examined, 180 are polymorphic, with 27 polymorphisms occurring at nonsynonymous, or replacement, sites. An average of nine amino ac...
متن کاملNucleotide variation and conservation at the dpp locus, a gene controlling early development in Drosophila.
A study of polymorphism and species divergence of the dpp gene of Drosophila has been made. Eighteen lines from a population of D. melanogaster were sequenced for 5200 bp of the Hin region of the gene, coding for the dpp polypeptide. A comparison was made with sequence from D. simulans. Ninety-six silent polymorphisms and three amino acid replacement polymorphisms were found. The overall silent...
متن کاملThe speciation history of Drosophila pseudoobscura and close relatives: inferences from DNA sequence variation at the period locus.
Thirty-five period locus sequences from Drosophila pseudoobscura and its siblings species, D. p. bogotana, D. persimilis, and D. miranda, were studied. A large amount of variation was found within D. pseudoobscura and D. persimilis, consistent with histories of large effective population sizes. D. p. bogotana, however, has a severe reduction in diversity. Combined analysis of per with two other...
متن کاملThe Speciation history of Drosophila Pseudoobscura and Close Relatives : Inferences from DNA Sequence Variation at the Period Locus Rong
Thirty-five period locus sequences from Drosophila pseudoobscura and its siblings species, D. p . bogotana, D. persirnilis, and D. rniranda, were studied. A large amount of variation was found within D. pseudoobscura and D. persirnilis, consistent with histories of large effective population sizes. D. p. bogotana, however, has a severe reduction in diversity. Combined analysis of perwith two ot...
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ژورنال
عنوان ژورنال: Genetics
سال: 1991
ISSN: 1943-2631
DOI: 10.1093/genetics/129.2.603a